Cadence Molecular Sciences (OpenEye) offers state-of-the art solutions in computational molecular design through consulting services, robust and scalable software for the desktop, and Orion®, a cloud-native, software-as-a-service (SaaS) molecular modeling platform. Combining massive scale computation and storage with powerful tools for data sharing, visualization and analysis in a customizable development environment, Orion offers unprecedented capabilities for the discovery of small molecule drugs, biologics, agrochemicals, and flavors and fragrances.